It's even easier with 6"
Especially if you use a corner litter tray like the one linked below. You put it in the corner where he goes to the toilet, on top of the bedding, with sand in it. The sand soaks up the pee and you just empty the litter tray 2 or 3 times a week and the rest of the cage stays clean and dry.
For the rest of the cage you can just "spot clean". ie take out the odd handful of soiled bedding and replace it with a clean handful, then mix it in a bit so it still smells familiar. But if you're using the litter tray you won't need to do a spot clean or clean out very often at all. I used to go 4 to 6 months before needing to change the substrate, with a litter tray. If you find there are quite a few poops taking over then you can just pick those out - but the odd one is ok as their poops aren't really dirty or smelly and they sometimes eat them, which is normal for them. In fact if you took every single poop out they might feel robbed of emergency food supplies
So when you do come to change the substrate you only change about half of of it. The way to do that is, keep back the bedding that is clean (which will actually be most of it, but the cleanest part of what you remove). Then you put some new bedding in and put the removed clean part back in on top, so it still smells familiar - this helps them be less stressed at a big clean out and change and it really does help. That top older bedding you can gradually spot clean out as and when necessary.
I hope all that makes sense but - the main thing is - don't throw away all their hoard or it makes them very anxious and develop odd behaviours. Providing you only give them a tiny bit of veg daily, they won't hoard it and will eat it straight away (ie a piece no bigger than their ear). So then they only hoard their dry hamster mix and any treats and they dry hoard stays fine for quite some time - unless they pee on it! But it sounds like your hamster is a clean little hamster who only pees in one corner
So then when you do come to change the substrate and put half back, at the same time, I tend to "prune" the hoard from underneath - ie take out the oldest food as that can start to go a bit stale or funny over time - and leave the top part of the hoard behind - the freshest bit. If the hoard is pee'd on then you'd have to remove it, but try and keep a few pieces of food that are dry left, so it still smells of the hamster, and add a handful of new food to replace the hoard - this keeps their stress levels down.
If the hamster has a nest, I usually leave that alone at clean out time as well. Again as long as it isn't pee'd in. I've had hamsters have the same nest for most of the time they are alive sometimes. They tend to refurbish it themselves if needed.
I hope this helps. Just ask if there's anything you're not sure of. What is your hammies name?
To answer the question though - there is no need to deep clean a cage, unless a hamster has has mites or some illness or disease.
Also it's best not to clean everything at the same time. So if you change the bedding (or half of it as above) then leave any other items until another week. Eg clean the wheel a week later. Other items in the cage often don't need cleaning very often and can just be done as and when.
Hamsters scent mark everything and rely on their scent marking to find their way around. If all their scent is removed in one go, they get very stressed and anxious that they have been invaded and it's no longer home - they might start bar chewing or exhibiting other stress behaviours.
